Last updated 5/23/22

COVID-19 treatments are not substitutes for COVID-19 vaccines. It is best to get vaccinated to prevent getting ill in the first place. 

What to know about COVID-19 treatments/therapies

If you test positive for COVID-19, different treatment options may be available to you. These treatments can reduce the risk of becoming seriously ill or hospitalized due to COVID-19. 

If you test positive for COVID-19, talk to your primary care provider or an urgent care provider right away to see if you qualify for treatment. This is especially important for those who are high risk and/or are not up-to-date on their COVID-19 vaccines. You must have a referral from a health care provider to access these treatments.  

Types of COVID-19 treatments

  • Antiviral medications may help you recover from COVID-19 faster or prevent you from becoming seriously ill. The medication can boost the immune system, helping it fight off COVID-19 infection. Antivirals are prescribed after a person has tested positive for COVID-19 and within 5 days of symptom onset. Paxlovid and Molnupiravi are two types of oral antiviral medications. 
  • Monoclonal antibody (mAb) treatment is an investigational therapy used to treat mild to moderate symptoms of COVID-19. It is approved for emergency use in non-hospitalized adults and pediatric patients who are at high risk for developing severe COVID-19 symptoms or the need for hospitalization. MAbs may be given as an infusion or a series of injections. 

Test to Treat

The new nationwide Test to Treat initiative provides quick access to free treatment for COVID-19. Through this program, people can get tested and – if they are positive and treatments are appropriate for them – receive a prescription from a health care provider, and have their prescription filled all at one location. 

These "One-Stop Test to Treat" sites are available at hundreds of locations nationwide, including pharmacy-based clinics, federally qualified health centers, and long-term care facilities. Search for a Test to Treat location here
A call center 1-800-232-0233 is available every day from 8:00 am to midnight ET to get help in more than 150 other languages. The Disability Information and Access Line is available to help people with disabilities access services. Call 1-888-677-1199, Monday-Friday from 9:00 am to 8:00 pm ET or email [email protected].

Important treatment notes

  • COVID-19 treatments are not substitutes for COVID-19 vaccines. If you aren't up-to-date on your vaccines, get vaccinated once you've recovered and are done with isolation.
  • You are still considered to be contagious while using treatment. Follow isolation guidance while using treatment.

Preventative Medication

Evusheld is an investigational medicine that can help protect you from getting COVID-19. You may be eligible for Evusheld if you:

  • Are moderately or severely immunocompromised and may not mount an adequate immune response to COVID-19 vaccination OR have a history of severe allergic reactions to COVID-19 vaccines, and 
  • Do not currently have COVID-19 and have not recently had close contact with someone with COVID-19, and
  • Are an adult or adolescent ages 12 years and older weighing at least 88 pounds (40 kg). 

Evusheld contains two different antibodies that can help prevent COVID-19. It must be given by your healthcare provider before exposure to COVID-19. Talk to your healthcare provider to find out if this option is right for you. Even if you receive Evusheld, taking multiple prevention steps can provide additional layers of protection from COVID-19.

Additional resources